Abstract

Objective: To carry out a study on Acinetobacter isolates from various clinical samples in a tertiary care hospital in India. To evaluate the preva lence of A. baumannii isolates, their antibiograms and clinical significance. Their contribution as causative agents of nosocomial infections has also been evaluated. Methods: The clinical specimens over a period of 12 months from January 2013 to December 2013 were an alyzed and the A. baumannii isolates obtained were further studied. Their antibiograms were studied and a clinical correlation was made to assess their pathogenic status. Results: A. baumannii was isolated in 417 samples out of 2116 gram negative isolates (19.7% pre valence) from the entire hospital. Maximum isolates were from ex udates & abscesses (41.5%) followed by respiratory secr etions (28%). Overall resistance of A .baumannii towards carbapenems was 25.65% from all hospital isolates. ICU isolates showed higher resistance (62.6%) as compared to Inpatient Department (35.5%) and Out-patient Depar tment (1.86%). Conclusions: In this study, A. baumannii isolates showed pathogenic potential, however a majority were found to be carbapenem sensitive. There was significant correlation between the carbapenem resistant strains is olated from the intensive care units, in-patient and out patient departments of the hospital.